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Our lab is interested in a multitude of projects to study Neurodegenerative Diseases (NDs) and Neurogenesis in relation to:
Our lab is interested in a multitude of projects to study Neurodegenerative Diseases (NDs) and Neurogenesis in relation to:
Proteostasis and Ribostasis
Proteostasis and Ribostasis
Neuroinflammatory and cellular degradative pathways in NDs
Biomolecular Condensates (Stress granules) and protein aggregates in NDs
Functional Genomics and Gene Regulation
Functional Genomics and Gene Regulation
Cis-regulatory structured ncRNAs in NDs
Alternative Splicing and mRNA Processing in NDs
LINE-1 retrotransposons and their role in NDs
Disease Modeling using iPSC derived 3D-Brain organoids
Disease Modeling using iPSC derived 3D-Brain organoids
Modeling neurodegenerative and neuropsychiatric disorders using patient-derived induced pluripotent stem cells (iPSCs)
Neuronal Mosaicism and Neurogenesis
Neuronal Mosaicism and Neurogenesis
Exploring the Genetic Diversity of the Brain to detect and analyze somatic mutations in individual brain cells, and to understand their role in brain development, aging, and disease
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